Skin anti-aging: Exosomes, peptides and spicules outperform retinol

Anti-aging skincare brand, Modern Molecules, in partnership with dermatologists from Korea, has launched the solution: REGENEX™ Renewal Serum. The anti-aging product uses the patent-pending REGENEX™ complex, which harnesses medical-grade technology developed to regenerate and heal burns – introducing a new category of medical cosmetics where healthcare innovation meets skincare aesthetics.  

Clinical studies conducted by the Korean Skin Research Centre, show that REGENEX™ Renewal Serum demonstrated remarkable results, surpassing retinol by 7.2 times in wrinkle reduction and 17 times in diminishing pigmentation after just 8 weeks of use.  The formulation integrates exosomes, spicules, and peptides —ingredients originally used to regenerate burnt skin. These medical technologies are now repurposed to tackle signs of aging.

Backed by an independent study from the Korean Skin Centre

REGENEX™ complex is the first product from Modern Molecules to utilize healthcare-derived technology in skincare. It was discovered by the company’s research team in Seoul, led by Dr Baek Ji Hwoon. The team has over 100 years of combined research experience and has published more than 200 peer-reviewed studies.

The REGENEX™ complex is clinically-proven to achieve:

• 7.2x better wrinkle reduction than retinol
• 17x better reduction in pigmentation and age spots
• Visible delay in aging by an average of 5.5 years after 8 weeks of daily use
• 65% increase in collagen production within 2 weeks
• 33% reduction in wrinkles within the first 2 weeks

Other acclaimed skincare experts on the discovery panel include Australia-based dermatology skin influencer Dr Davin Lim (@drdavinlim) who has over 900k followers on both Instagram and YouTube; LinkedIn Beauty Top Voice cosmetic scientist Manessa Lormejuste, and Singapore aesthetic doctor Dr Vicki Leong.

The complex combines three core technologies that work in tandem to reverse the effects of aging:

• - Exosomes: These powerful nanoparticles signal skin cells to regenerate and initiate the cell renewal process, boosting collagen production for plumper, more youthful skin.
• - Spicules: Natural liquid microneedles create microchannels in the skin, allowing exosomes to penetrate deeper. Unlike most skincare products that remain on the surface, this technology regenerates skin from within, ensuring long-term results.
• - Peptide Complex: Clinically proven wrinkle-reversal peptides are small proteins that smooth wrinkles and enhance skin elasticity, leading to younger, healthier-looking skin.

Dr. Baek, who led the development of the REGENEX™ technology, said: "REGENEX™ Renewal Serum represents a significant advancement in anti-aging and delivers performance that has shown statistically significant superior efficacy versus retinol. It is an innovation that has been used to treat burn wounds with powerful regenerative properties. Harnessing this technology once used to regenerate burnt skin, we applied it to aged skin and were amazed to discover that it can trigger skin cell regeneration from deep within, reducing the appearance of wrinkles and pigmentation while improving overall skin texture."

Jo T, 33, a clinical trial participant, shared her experience: "As someone who's tried many anti-aging products with little success, I was hesitant at first. Retinol has always irritated my skin, so I didn't expect much. But the REGENEX™ Renewal Serum surprised me right away. It felt light, absorbed quickly, and didn't leave my skin feeling greasy. Within two weeks, I started noticing my skin was changing. My skin felt firmer, and after eight weeks, the fine lines and wrinkles around my eyes and mouth had visibly reduced. What stood out most was how much smoother and younger my skin looked overall—like it had turned back the clock. I can confidently say this serum has made a huge difference in my routine, and I'll definitely be continuing with it."

Setting a new standard in anti-aging technology 

REGENEX™ Renewal Serum is the result of decades of research and innovation from Modern Molecules' team of renowned dermatologists. More than just a skincare product, this serum represents a ground-breaking advancement in medical cosmetics, bringing healthcare technology originally developed to help burn victims regenerate new skin into the consumer skincare market. Designed to rejuvenate skin from the inside out, it effectively boosts collagen production, strengthens the skin barrier, and improves elasticity, providing visible, long-term anti-aging results.

Modern Molecules renewal serum: Before and after results following 8 weeks of clinical trials

In five independent clinical studies, REGENEX™ Renewal Serum was shown to significantly outperform traditional retinol treatments. During a user trial involving 25 participants aged 30-52, all with varying degrees of visible aging, key findings included:

• - 89% agreed that REGENEX™ was more effective than retinol
• - 97% observed firmer, plumper skin
• - 93% saw a more youthful complexion
• - 97% noted improvements in skin tone and texture
• - 80% witnessed a reduction in fine lines and wrinkles
• - 73% experienced reduced pigmentation and age spots.